The purpose of this study was to estimate the consumption prevalence of vitamin and mineral supplements as healthfunctional foods (VM-HFF) and to examine the factors associated with VM-HFF consumption behaviors in adolescents. Atotal of 1,407 adolescents attending middle or high schools from various cities and rural communities in Korea participatedin this study. The prevalence of VM-HFF consumption was 41.7%, with boys showing a higher consumption than girls(p<0.01). VM-HFF consumption was higher in families with higher socioeconomic status and for families with parents thatexhibited higher concerns about their child’s health, growth, and nutritional intake (p<0.001). Most consumers of VM-HFFconsumed HFFs ‘when healthy’ (50.1%), and acquired nutritional information from ‘their families & relatives’ (50.9%).Most consumers responded that VM-HFF was ‘a little effective’ (54.3%), followed by ‘no obvious effects’ (37.1%), and ‘veryeffective’ (7.4%). The effectiveness of consuming VM-HFF was mainly for ‘fatigue recovery’ (39.0%) and ‘healthimprovement’ (28.2%). Most consumers purchased HFFs at ‘pharmacies & oriental medicine clinics’ (53.8%) and at ‘healthfunctional food stores’ (18.8%). Most consumers ‘occasionally’ (51.1%) or ‘seldom’ (27.3%) checked nutrition facts whenpurchasing, with 58.9% of consumers understanding the nutritional label for ‘the most part’, but only 8.7% of themunderstanding it ‘very well’. Among the VM-HFF, consumers preferred calcium- and vitamin C-supplements. Consumers’mini-dietary assessment scores were higher than those of non-consumers. The results above showed that VM-HFFconsumption was widely spread among adolescents, but few consumers checked and understood the nutrition label whenthey purchased VM-HFF, and were highly dependent on the advice and information from non-professional nutritionists,such as families & relatives. Therefore, it is necessary to educate adolescents to help them read nutrition labels and selectthe proper VM-HFF.